一分赛车

生物科学门户网站
dxdlzg.com

CRISPR辅助新方法可检测活细胞中的RNA结合蛋白

jinguankexuejiamenrengbuwanquanlejiernafenzideduoyangxing,danjuxinyutamenjiehededanbaizhi(chengweirnajiehedanbai)yuxuduojibingdexingchengyouguan。xianggangchengshidaxue(cityu)shengwuyixuekexuejialingdaodeyixiangyanjiukaifaleyizhongmingweicarpiddexinxingjiancefangfa,yongyujiandinghuoxibaozhongtedingrnadejiehedanbai。youwangjianggaichuangxinjishuyingyongyugezhongxibaoyanjiu,congjiandingaizhengzhenduandeshengwubiaozhiwudaojiancezhiliaobingduxingjibingdeqianzaiyaowubabiao。

zheixiangyanjiuyouchengdashengwuyixuexi(bms)deyanjianboshi,zhangliangboshihechenkuimingboshiyuzhuyaolaizixianxibeidaxuedekexuejiahezuojinxing。tamendefaxianfabiaozaikexuezazhi《ziranfangfa》shang,biaotiwei“ crisprfuzhujiancehuoxibaozhongrna-danbaizhixianghuzuoyong”。

jiehedanbaijuedingrnagongneng

fenzishengwuxuedezhongxinjiaotiaobiaoming,dnabeizhuanluweirna,rnabeifanyiweidanbaizhi。danshijishang,zhiyoudayue2%dernabianmadanbaizhi。qiyu98%defeibianmarna(ncrna)yinqishenmidegongnengerbeishiwei“anwuzhi”。

jinnianlai,kexuejiamenfuchulehenduonulilaijieshiqishijigongneng,youqishizhangdefeibianmarna(lncrna,yizhizhangduchaoguo200gehegansuandencrna)。lncrnayibeiguangfanjieshouweicanyujiyinbiaodadiaokongdezhongyaoxibaochengfen。yanboshishuo: “ lncrnashizuiyouqudernazhonglei。” zheiyeshigaituanduixuanzelncrnazuoweiyanjiuduixiangdeyuanyin。

一分赛车jinguanlncrnabuhuichanshengdanbaizhi,dantamenhuiyudanbaizhifanying,xianghuzuoyongjiangjuedingqigongneng。yinci,jiehedanbaidejiandingduiyulijielncrnagongnengzhiguanzhongyao。raner,dangqiandefangfabiaoxianchuxiangdangdadejuxianxing,liruchanshengjiayangxingxinhao,bingqiebunengzaihuoxibaozhongwancheng。

carpiddelianggebuzhou: daohangheshengwusubiaoji

一分赛车weilekefuxianyoufangfadejuxianxing,yanjiutuanduitichuleyizhongxinyingdefangfa,gaifangfajiangxianyoudezuixinjiyinbianjijishucrispr / dcasrxxitongyongyurnabaxiang,bingjianglinjinshengwusubiaojijishuyongyujiandinghuoxibaozhongdedanbaizhi-danbaizhixianghuzuoyong。

gaituanduijiangxinfangfamingmingweicarpid,tashicrisprfuzhurna-danbaizhixianghuzuoyongjiancedesuoxie。yanboshishuo: “ carpidkeyimingandijiancerenhezhangduhuonongdudernajiehedanbai,erdaduoshuqitafangfazhinengyingyongyuhenzhangdefeibianmarna。”

gaifangfayouliangbufenzucheng: daohanghelinjinshengwusubiaoji。shouxian,gaituanduicaiyongcrispr / casrxxitongjinxingdaohang,yibiancarpidzujian(baokuochengweibasude“biaojigongju”)keyikaojinmubiaorna。basushiyizhonggongchenghuadeshengwusulianjiemei,shiyizhongjiangshengwusu(yizhongjuyouqiangjiehelideweishengsu)tianjiadaoyumubiaornajiehededanbaizhishangdemei。zheiyang,jiangbiaojijiejinmubiaornadeneixiedanbaizhi。

一分赛车zai“biaoji”zhihou,yanjiuxiaozusuihoushiyongleyizhongchengweilianmeiqinhesudeshengwusujiehedanbailaijiandingneixiebeibasubiaojidedanbai。zheiyang,jiehedanbairongyibeijieshi。

一分赛车duibutongzhangdudelncrnajuyougaodudeteyixingheshiyongxing

weileceshicarpiddeteyixing,yanjiuxiaozujiangqiyingyongyusanzhongbutongdelncrna,jidancr,xisthemalat1。shiyanjieguobiaomingjiehedanbaimeiyoutaiduodezhongdie。zheizhengminglecarpidfangfaduibutongzhangduhebiaodashuipingdelncrnadegaoduteyixingheshiyongxing。

一分赛车yanboshijieshishuo: “zhisuoyidadaorucigaodeteyixing,shiyinweicrisprdedaohangfeichangjingque。yifensaicheshenzhikeyizhunquedihuodedanbaizhijiehefashengzairnanayibufendexinxi。”

一分赛车erqie,carpidbuhuiyingxiangbaxibaodeshenglizhuangkuang,bingqiezaizhenggeguochenghou,gaixibaorengranhuozhe,juyouzhengchangdejiyinbiaodageju。zhangboshibuchongshuo: “tongguozheizhongxinfangfa,ruguoyifensaichezaibutongshijianjianchaxiangtongdernababiao,yifensaichekeyihuodedongtaijieguo。”

一分赛车zaizhangboshikaifadedanbaizhizuxue(danbaizhifenxi)jishudezhichixia,yanjiuxiaozunenggoufaxianheyanzhengburudongwuxibaozhonglncrnadelianggeyiqianweibiaozhengdejiehedanbai。

郑重声明: 本文版权所有:一分赛车_一分赛车网址_唯一官网

一分赛车_一分赛车网址_唯一官网 香港赛马_香港赛马官网-欢迎您 时时彩_时时彩欢彩网_最佳信誉官网 时时彩_腾讯时时彩-官方认证 秒速飞艇_秒速飞艇彩票-欢迎您 北京pk10,北京pk10官网-欢迎您 德国飞艇_哪里可以买德国飞艇-专业购彩APP 五分赛车_五分赛车开奖官网-点击进入>! 上海时时乐_上海时时乐下注_主页 秒速赛车_秒速赛车app|官方登录平台 秒速赛车_秒速赛车开户|【官网】