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粪便微生物使诊断更具挑战性

洛杉矶-(2020年7月1日)据世界卫生组织称,慢性肝病是全球主要的公共卫生问题,估计影响8.44亿人。它是澳大利亚,英国和美国的主要死亡原因之一。同时,这既难以管理,也没有FDA批准的抗纤维化肝疗法。微生物组-居住在肠道中的微生物的复杂集合-可能是健康的意外指标。现在,Salk研究所和加州大学圣地亚哥分校的科学家组成的协作团队已经创建了一种基于微生物组的新型诊断工具,该工具能够以最佳医师的身份准确,快速且廉价地识别人类患者90%的肝纤维化和肝硬化。

一分赛车2020nian6yue30rizaixianshangxiangxijieshaolezheizhongfeiqinruxingfangfayilaiyuyizhongsuanfalaifenxihuanzhefenbianyangben-gaiyangbenbaohanchangdaoneishenghuodehenji-bingkenenggaishanganzangjibingdehuanzhehulihezhiliaoxiaoguo。xibaodaixie。

一分赛车“weishengwuzushiyizhongdongtaideshengmingchuanganqi,keyijiancechurentijiankanghejibingdexiweibianhua,yinci,takeyizhunqueduchurentidejiankangzhuangkuang,”《tongxun》zazhizuozhejianzuozhesaerke·luonade·aiwensishuoyizi。“youyuzheizhongzhenduangongjukuaisuqiechengbendilian,yincikenenghuibeiguangfanshiyong,youqishizaiqueshaozhuankezhensuoheyishengdexuduodiqu。jiandandishuo,takenenghuizhenzhenggaibianyouxiguize,duishijiechanshengyingxiang。”

feijiujingxingzhifangxingganbing(nafld)shiquanqiufanweineimanxingganbingdezhuyaoyuanyin,suizheganzangkaishixingchengbahenhexibaosiwang,feijiujingxingzhifangganbingkenenghuifazhanweiganxianweihua,ganyinghuaheqianzaideaizheng。danshiquefayongyuganxianweihuaheganyinghuadezhenduangongju。huozuzhijianchashiqinruxingde,kenenghuiloudiaoganzangdeshoushangquyu,ermriangguiqiezainongcundiqutongchangbukeyong。weileyingduizheixietiaozhan,yanjiutuanduiduiweishengwuzujinxingletansuo,yicilaimanzupoqiexuyaojinxingxinceshiyijiandinggaoweihuanzhedexuqiu。

一分赛车gaiyanjiudehezhuzhe,salkdegaojikexuejiamichael downesshuo: “yifensaicheshitugenjugaijibingde'weishengwuzutezheng',kaifayizhongzhenduiganxianweihuaheganyinghuadetongyong,feiqinruxingceshi。”

gaituanduiyujiazhoudaxueshengdiyagefenxiaoshengdiyagefenxiaodekexuejiahezuo,youhualeyizhongchengweijiqixuexidejisuanfangfa,yijiyuhuanzhezufenbianyangbenzhongcunzaide19zhongxijunlaifaxianfuzadejibingtezheng。qianmingyoubutongshuliangdexijunzucheng,chuangjianleyongyushibieganxianweihuaheganyinghuadetongyongzhiwen。gaiyanjiubaokuolaizijiankanghehuanbingjiatingchengyuande163gelinchuangyangben,yijiandingzhishiganbingdebianliang。

一分赛车yanjiurenyuanliyongweishengwujiyinzufenxihefenbianyangbendaixiechanwudeshuju,faxianleyuganyinghuazhenduanxiangguandeweishengwuzutezheng,zhunqueduda94%。weishengwuzutezhenghaikeyiquedingganxianweihuadejieduan,zheikeyishiyishenggenjuhuanzhedejibingjieduanduiqijinxingfenjibinggaishanzhiliaocelve。

gailunwendediyizuozhe,gaiyanjiusuodeboshihouyanjiuyuantae gyu ohshuo: “zheixiefaxianbiaoming,keyishiyongjiqixuexilaishibiekeyongyuzhunquezhenduanjibing(liruganyinghua)detongyongtezheng。”aiwensishiyanshi。“yifensaichefaxiandemoshifanyingleweishengwuzudefuzaxingyijichangdaojiankangkenengruheyingxiangjibing。”

ranhou,yanjiurenyuanjiangtamendeweishengwuzuqianmingyingyongyulaizizhongguoheyidalidelianggedulirenqun。gaituanduideqianmingkeyizhunquedishibie90%yishangdehuanzhedeganyinghua,congeryanzhenglegaisuanfazaibutongyichuanxueheyinshifangmiandegongxiaohezhunquexing。

“zhidezhuyideshi,laizijuzhuzainanjiazhoudeganyinghuahuanzhedechangdaoweishengwuzutezhengnenggouyucejuzhuzaizhongguoheyidalidelianggeduliduiliezhongdeganyinghua。zheishuomingleshangweibeifaxiandexinfaxian。changdaoweishengwuzulaizhenduanganbingbingduiqijinxingfengxianfenceng”,jiazhoudaxueshengdiyagefenxiaoyixueyuannafldyanjiuzhongxinzhuren,zuozhezhiyirohit loombashuo。“yifensaicherenweishiyongweishengwuzuzuoweizhenduangongjudeliliangcaiganggangkaishibeiyishidao。”

weilai,kexuejiajiangtongguoceshiweishengwuzudehuifubufenshifoudaozhijibingxiaotuihuoquchumouxiexijunshiqiehua,laijianyanweishengwuzuyuganzangjibingzhijiandeyinguoguanxi。yanjiuxiaozuhaixiwangzheizhongfangfakeyiyongyubiaozhengqitajibing,liruyanzhengxingchangbing,jiechangai,aercihaimoshibingheqitakenengshoudaoweishengwuzushidiaoyingxiangdejibing。

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